Water-soluble vitamins absorb best on an empty stomach.
That means taking them first thing in the morning, 30 minutes prior to eating, or two hours after a meal. ... Since your body doesn't store these vitamins, it's a good idea to incorporate them into your diet or take a supplement.
You definitely should take your multivitamin with food, though, since some of the vitamins in it most likely are fat-soluble. Some larger multivitamin supplements cancause stomach upset if taken on an empty stomach, as well.Sep 12, 2018
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